Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247100 | 1.00 | TDP1 (0.40) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL247099 | 0.91 | TDP1 (0.40) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL1157238 | 0.88 | TDP1 (0.37) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL1673996 | 0.87 | TDP1 (0.47) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL245087 | 0.85 | ATM (0.37) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL27488778 | 0.85 | TDP1 (0.37) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL27819527 | 0.85 | ATM (0.37) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL1870707 | 0.85 | ATM (0.37) | TDP1ATMALDH1A1ESR1CYP3A4 | |
| SCHEMBL7647735 | 0.84 | CHRM2 (0.39) | ALDH1A1ESR1CYP3A4ESR2MAPT | |
| SCHEMBL1681408 | 0.84 | KDM4E (0.45) | TDP1ATMALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174935-B1 | COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-06-21 | — | — | EP | disclosed |
| EP-3174934-B1 | COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-06-14 | — | — | EP | disclosed |
| EP-3227374-B1 | COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-06-01 | — | — | EP | disclosed |