Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | BLVRB | P30043 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564256 | 0.80 | CA12 (0.53) | MEN1KMT2ATSHRALDH1A1PTGS2 | |
| SCHEMBL137145 | 0.79 | MEN1 (0.85) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL137146 | 0.79 | MEN1 (0.85) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL15339774 | 0.79 | MEN1 (0.85) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL28847216 | 0.78 | MEN1 (0.82) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL20483076 | 0.77 | IDE (0.51) | MEN1KMT2ATDP1CYP2D6CYP2C19 | |
| SCHEMBL252921 | 0.76 | LMNA (0.59) | MEN1KMT2AHTTTSHRCYP2C19 | |
| SCHEMBL16937237 | 0.75 | IDE (0.66) | MEN1KMT2ATDP1THRBALDH1A1 | |
| SCHEMBL29950230 | 0.75 | MEN1 (0.61) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL27985065 | 0.75 | MEN1 (0.61) | MEN1KMT2ABLVRBPDE4AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2549999-A1 | AZO COMPOUNDS REDUCING FORMATION AND TOXICITY OF AMYLOID BETA AGGREGATION INTERMEDIATES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011117305-A1 | AZO COMPOUNDS REDUCING FORMATION AND TOXICITY OF AMYLOID BETA AGGREGATION INTERMEDIATES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368558-A1 | Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates | Mdc Max-Delbrück-Centrum Für Molekulare Medizin Berlin - Buch (DE) | 2011-09-28 | — | — | EP | disclosed |