Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711531 | 0.88 | DRD2 (0.33) | DRD2PIK3CD | |
| SCHEMBL12735346 | 0.79 | PIK3CD (0.33) | POLBPIK3CD | |
| SCHEMBL8260056 | 0.79 | HTR2A (0.39) | PIK3CD | |
| SCHEMBL12267884 | 0.79 | HTR2A (0.39) | PIK3CD | |
| SCHEMBL14329347 | 0.79 | HTR2A (0.39) | PIK3CD | |
| SCHEMBL20940079 | 0.78 | LTA4H (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20522860 | 0.74 | TACR1 (0.48) | DRD2 | |
| SCHEMBL2659902 | 0.74 | TACR1 (0.48) | DRD2 | |
| SCHEMBL24711528 | 0.74 | DRD2 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20922156 | 0.74 | MEN1 (0.35) | POLBDRD3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261243-A1 | COMBINATION THERAPIES WITH SETD2 INHIBITORS | Epizyme, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |