SCHEMBL24712962

SCHEMBL24712962

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-n4c5ccccc5c5cc(C6(c7ccccc7)c7ccccc7-c7ccccc76)ccc54)cc3)cc21

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TSPO P30536 1/20 0.31
▸ HDAC4 P56524 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18118773 0.97 KDM4E (0.32) TSPOKDM4EATML3MBTL1
SCHEMBL22150968 0.95 KDM4E (0.32) HDAC4KDM4EATML3MBTL1
SCHEMBL15866648 0.95 KDM4E (0.33) HDAC4KDM4EATML3MBTL1
SCHEMBL17804750 0.95 KDM4E (0.33) HDAC4KDM4EATML3MBTL1
SCHEMBL24712308 0.94 ESR1 (0.31) —
SCHEMBL17816624 0.94 KDM4E (0.33) HDAC4KDM4EATML3MBTL1
SCHEMBL24712718 0.94 ESR1 (0.30) —
SCHEMBL24712207 0.94 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL17742412 0.93 KDM4E (0.33) HDAC4KDM4EATML3MBTL1
SCHEMBL24712289 0.93 ESR1 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF CHANGCHUN HYPERIONS TECH CO LTD (CN) 2023-01-26 — — US disclosed
EP-4101841-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF Changchun Hyperions Technology Co., Ltd. (CN) 2022-12-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF TRDMT1, TCF4, TRMT1 TSPO 537/4885HDAC4 2996/4885KDM4E 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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