SCHEMBL24712997

SCHEMBL24712997

Cc1ccc(-c2cc(-c3ccccc3)cc(-c3ccccc3)c2)c2c1[C@@]1(C)CCc3ccc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)c(c31)CNC2

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.36
CD274 Q9NZQ7 1/20 0.31
TDP2 O95551 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24713003 0.84 CD274 (0.34) PRCPCD274
SCHEMBL24712998 0.81 PRCP (0.42) PRCPTDP2
SCHEMBL24712995 0.73 PRCP (0.50) PRCPTDP2
SCHEMBL24712922 0.70 MEN1 (0.33) PRCP
SCHEMBL24712918 0.67 HTR5A (0.35) CD274
SCHEMBL24713002 0.66 MEN1 (0.35)
SCHEMBL24712996 0.64 GSTP1 (0.37) PRCPCD274
SCHEMBL18554654 0.60 CD274 (0.45) PRCPCD274
SCHEMBL24712920 0.60 PRNP (0.36) CD274TDP2
SCHEMBL20374194 0.58 PRCP (0.71) PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022218391-A1 CHIRAL SPIRO AMMONIUM SALT COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 西湖大学 2022-10-20 WO disclosed