Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713002 | 0.95 | MEN1 (0.35) | MEN1KMT2AOPRM1CNR1CNR2 | |
| SCHEMBL24712998 | 0.82 | PRCP (0.42) | CLK4DYRK1BPRCPPARP10PARP11 | |
| SCHEMBL24712995 | 0.81 | PRCP (0.50) | PRCPPARP10PARP11 | |
| SCHEMBL24712920 | 0.78 | PRNP (0.36) | — | |
| SCHEMBL24712996 | 0.77 | GSTP1 (0.37) | PRCP | |
| SCHEMBL24712997 | 0.70 | PRCP (0.36) | PRCP | |
| SCHEMBL24713003 | 0.66 | CD274 (0.34) | PRCP | |
| SCHEMBL24712806 | 0.63 | CD44 (0.41) | MEN1KMT2A | |
| SCHEMBL24712809 | 0.62 | MAPT (0.36) | MEN1KMT2APRCP | |
| SCHEMBL30735648 | 0.62 | RXRA (0.33) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218391-A1 | CHIRAL SPIRO AMMONIUM SALT COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 西湖大学 | 2022-10-20 | — | — | WO | disclosed |