Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24712995 | 0.81 | PRCP (0.50) | CYP3A4HTR1AHTR7TDP2 | |
| SCHEMBL24712922 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL24712996 | 0.77 | GSTP1 (0.37) | CD274 | |
| SCHEMBL24712998 | 0.74 | PRCP (0.42) | CYP3A4TDP2 | |
| SCHEMBL24713002 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL30735913 | 0.65 | CYP3A4 (0.42) | CYP3A4HTR1A | |
| SCHEMBL31070657 | 0.63 | CHRNB2 (0.48) | CYP3A4CD274TDP2 | |
| SCHEMBL28803678 | 0.63 | ABL1 (0.46) | MAPTHTR1AHTR7 | |
| SCHEMBL13647384 | 0.62 | ADRA2A (0.49) | CYP3A4HTR1A | |
| SCHEMBL24712806 | 0.62 | CD44 (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218391-A1 | CHIRAL SPIRO AMMONIUM SALT COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 西湖大学 | 2022-10-20 | — | — | WO | disclosed |