SCHEMBL24713036

SCHEMBL24713036

CC[C@@H]1NC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)CNC(=O)CN)CSSC[C@@H](C(N)=O)NC1=O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 11/20 0.51
▸ SSTR1 P30872 1/20 0.47
▸ SSTR2 P30874 1/20 0.47
▸ SSTR4 P31391 1/20 0.47
▸ SSTR3 P32745 1/20 0.47
▸ SSTR5 P35346 1/20 0.47
▸ CTSG P08311 1/20 0.45
▸ TNFSF11 O14788 1/20 0.45
▸ MC4R P32245 3/20 0.45
▸ MC5R P33032 3/20 0.45
▸ MC3R P41968 3/20 0.45
▸ MC1R Q01726 3/20 0.45
▸ PLAU P00749 1/20 0.44
▸ CACNA1B Q00975 1/20 0.44
▸ TBXA2R P21731 1/20 0.43
▸ AVPR1A P37288 1/20 0.43
▸ PDE4D Q08499 1/20 0.43
▸ PDE3A Q14432 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24713050 0.91 SSTR2 (0.53) TSLPSSTR1SSTR2SSTR4SSTR3
SCHEMBL24713080 0.85 SSTR2 (0.51) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL19806987 0.81 PIN1 (0.51) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12146083 0.80 TSLP (0.56) TSLPCTSGMC4RMC5RMC3R
SCHEMBL18767059 0.80 CACNA1B (0.58) TSLPCACNA1B
SCHEMBL12315562 0.80 ITGB3 (0.48) TSLPMC4RMC5RMC3RMC1R
SCHEMBL19807066 0.79 PIN1 (0.49) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL23018583 0.79 TSLP (0.52) TSLPMC4RMC5RMC3RMC1R
SCHEMBL14585808 0.79 MC4R (0.57) MC4RMC5RMC3RMC1R
SCHEMBL19605463 0.79 MC4R (0.57) MC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220387608-A1 ADRENOMEDULLIN-ANALOGUES FOR LONG-TERM STABILIZATION AND THEIR USE BAYER AKTIENGESELLSCHAFT (DE) 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220387608-A1 ADRENOMEDULLIN-ANALOGUES FOR LONG-TERM STABILIZATION AND THEIR USE VEGFA, ADM2, SERPINA6 TSLP 173/4885SSTR1 787/4885SSTR2 692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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