Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824962 | 1.00 | ALDH1A1 (0.33) | ALDH1A1GAAHPGDCA12CA1 | |
| SCHEMBL24713034 | 0.87 | HDAC1 (0.35) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL30824955 | 0.87 | HDAC1 (0.35) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL30824948 | 0.87 | FFAR1 (0.36) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL24713337 | 0.87 | FFAR1 (0.36) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL24713062 | 0.86 | HDAC1 (0.34) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL30824944 | 0.86 | HDAC1 (0.34) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL24713072 | 0.84 | HDAC1 (0.33) | HDAC1HDAC6HDAC5 | |
| SCHEMBL24713052 | 0.82 | HDAC1 (0.37) | HDAC1HDAC6HDAC5 | |
| SCHEMBL24713027 | 0.79 | HDAC1 (0.33) | HDAC1HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220372045-A1 | DEUTERATED COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2022-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220372045-A1 | DEUTERATED COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HIRIP3 | ALDH1A1 4688/4885GAA 1657/4885HPGD 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.