Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713034 | 1.00 | HDAC1 (0.35) | HDAC1HDAC6HDAC5FFAR1PDE10A | |
| SCHEMBL24713062 | 0.92 | HDAC1 (0.34) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL30824944 | 0.92 | HDAC1 (0.34) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL30824948 | 0.90 | FFAR1 (0.36) | HDAC1HDAC6HDAC5FFAR1PDE10A | |
| SCHEMBL24713337 | 0.90 | FFAR1 (0.36) | HDAC1HDAC6HDAC5FFAR1PDE10A | |
| SCHEMBL24713124 | 0.87 | ALDH1A1 (0.33) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL30824962 | 0.87 | ALDH1A1 (0.33) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL24713072 | 0.87 | HDAC1 (0.33) | HDAC1HDAC6HDAC5 | |
| SCHEMBL24713052 | 0.87 | HDAC1 (0.37) | HDAC1HDAC6HDAC5FFAR1 | |
| SCHEMBL24713027 | 0.82 | HDAC1 (0.33) | HDAC1HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606570-B2 | Deuterated compounds and imaging agents for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| CN-117545512-A | Deuterated compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12606570-B2 | Deuterated compounds and imaging agents for imaging huntingtin protein | HTT, HYPK, ATXN2 | HDAC1 2530/4885HDAC6 161/4885HDAC5 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.