Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471392 | 1.00 | ABCB1 (0.42) | ABCB1KDM4E | |
| SCHEMBL4020277 | 0.81 | HTR2A (0.32) | — | |
| SCHEMBL4848406 | 0.81 | HTR2A (0.32) | — | |
| SCHEMBL9200651 | 0.80 | ABCB1 (0.44) | ABCB1KDM4E | |
| SCHEMBL481900 | 0.80 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9363607 | 0.80 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 0.80 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL4023253 | 0.80 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL482249 | 0.80 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL6273195 | 0.80 | ABCB1 (0.56) | ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546136-B1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING IMIDAZOLE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RES INST CHEM TECH (KR) | 2011-10-05 | — | — | EP | disclosed |
| US-7279497-B2 | Benzopyran derivatives substituted with secondary amines including imidazole, their preparation and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-10-09 | — | — | US | disclosed |
| US-20050267188-A1 | Therapy of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, for protection of heart, neuronal cells, brain injury, organs for preservation or in cardiovascular surgery against ischemia-reperfusion injury or oxidative stress | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-12-01 | — | — | US | disclosed |
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | disclosed |
| US-5236935-A | Hypotensive agents | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-08-17 | — | — | US | disclosed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267188-A1 | Therapy of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, for protection of heart, neuronal cells, brain injury, organs for preservation or in cardiovascular surgery against ischemia-reperfusion injury or oxidative stress | FLT4, ALDH1A2, KDR | ABCB1 2924/4885KDM4E 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.