Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155098 | 0.81 | ERN1 (0.47) | TAAR1PRMT6ERN1PGRKEAP1 | |
| SCHEMBL15519549 | 0.80 | TAAR1 (0.61) | TAAR1HDAC2PRMT6ERN1PGR | |
| SCHEMBL3468657 | 0.79 | TAAR1 (0.55) | TAAR1HDAC2PRMT6ERN1PGR | |
| SCHEMBL24196355 | 0.75 | ALDH1A1 (0.57) | TAAR1HDAC2PRMT6ERN1PGR | |
| SCHEMBL12121599 | 0.75 | ERN1 (0.62) | TAAR1HDAC2ERN1PGRKEAP1 | |
| SCHEMBL26673582 | 0.75 | TAAR1 (0.54) | TAAR1HDAC2PRMT6ERN1PGR | |
| SCHEMBL19475516 | 0.75 | ADORA2A (0.56) | TAAR1ERN1ADORA2A | |
| SCHEMBL30820503 | 0.75 | ADORA2A (0.56) | TAAR1ERN1ADORA2A | |
| SCHEMBL20163156 | 0.73 | HDAC2 (0.60) | TAAR1HDAC2ERN1KEAP1 | |
| SCHEMBL23154128 | 0.72 | HDAC2 (0.49) | TAAR1HDAC2PRMT6ERN1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |