Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 11/20 | 0.45 |
| ▸ | KDR | P35968 | 8/20 | 0.44 |
| ▸ | RET | P07949 | 7/20 | 0.44 |
| ▸ | KIF5B | P33176 | 6/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24715206 | 0.84 | KDR (0.53) | EGFRKDRRETKIF5BFLT1 | |
| SCHEMBL24714929 | 0.83 | EGFR (0.54) | MAPK1EGFRKDRRETKIF5B | |
| SCHEMBL24713874 | 0.82 | KDR (0.52) | MAPK1EGFRKDRRETKIF5B | |
| SCHEMBL24713875 | 0.80 | EGFR (0.55) | MAPK1EGFRKDRRETKIF5B | |
| SCHEMBL24714943 | 0.79 | EGFR (0.56) | MAPK1EGFRKDRRETKIF5B | |
| SCHEMBL24714641 | 0.79 | EGFR (0.56) | MAPK1EGFRKDRRETKIF5B | |
| SCHEMBL24714666 | 0.75 | KDR (0.46) | EGFRKDRRETKIF5BFLT1 | |
| SCHEMBL24714671 | 0.75 | KDR (0.49) | EGFRKDRRETKIF5BFLT1 | |
| SCHEMBL24714485 | 0.74 | KDR (0.60) | EGFRKDRRETKIF5BFLT1 | |
| SCHEMBL24714620 | 0.73 | KDR (0.48) | MAPK1EGFRKDRRETKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |