Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2518133 | 0.84 | PAX8 (0.59) | PAX8KDM4EL3MBTL1CTSBALOX15 | |
| SCHEMBL3590445 | 0.75 | PAX8 (0.56) | PAX8KDM4EL3MBTL1CTSB | |
| SCHEMBL27190170 | 0.74 | KDM4E (0.67) | KDM4EL3MBTL1CTSBCYP2D6HIF1A | |
| Hydrochloric Acid SCHEMBL27190054 | 0.73 | ALDH1A1 (0.65) | KDM4EL3MBTL1CTSBCYP2D6HIF1A | |
| SCHEMBL1520610 | 0.73 | PAX8 (1.00) | PAX8KDM4EL3MBTL1ALOX15CYP2D6 | |
| SCHEMBL15217627 | 0.73 | KDM4E (0.68) | PAX8KDM4EL3MBTL1ALOX15CYP2D6 | |
| SCHEMBL17278913 | 0.72 | ALDH1A1 (0.52) | PAX8KDM4EL3MBTL1CTSBALOX15 | |
| SCHEMBL11221828 | 0.72 | KDM4E (0.61) | PAX8KDM4EL3MBTL1ALOX15CYP2D6 | |
| SCHEMBL28744388 | 0.70 | PAX8 (0.59) | PAX8KDM4EALOX15CYP2D6HIF1A | |
| SCHEMBL8923294 | 0.70 | PAX8 (0.77) | PAX8KDM4EL3MBTL1ALOX15CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |