SCHEMBL8923294

SCHEMBL8923294

Oc1cccc2c(Cc3ccccc3)ccnc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.77
KDM4E B2RXH2 8/20 0.68
TP53 P04637 4/20 0.68
LMNA P02545 4/20 0.68
MAPT P10636 3/20 0.68
TSHR P16473 2/20 0.68
ALOX12 P18054 2/20 0.68
L3MBTL1 Q9Y468 6/20 0.54
ALOX15 P16050 3/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
HIF1A Q16665 1/20 0.54
RAB9A P51151 3/20 0.52
MAOB P27338 3/20 0.52
HTT P42858 3/20 0.52
NPC1 O15118 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAOA P21397 2/20 0.52
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1520610 0.87 PAX8 (1.00) PAX8KDM4ETP53LMNAMAPT
SCHEMBL10579569 0.86 KDM4E (0.78) PAX8KDM4ETP53LMNAMAPT
SCHEMBL27851196 0.83 PAX8 (0.60) PAX8KDM4ETP53LMNAMAPT
SCHEMBL16965433 0.82 ALOX15 (0.80) PAX8KDM4ETP53LMNAMAPT
SCHEMBL16132606 0.81 KDM4E (1.00) PAX8KDM4ETP53LMNAMAPT
SCHEMBL16965245 0.78 KDM4E (0.74) PAX8KDM4ETP53LMNAMAPT
SCHEMBL1714724 0.78 KDM4E (0.74) PAX8KDM4ETP53LMNAMAPT
SCHEMBL29203716 0.78 KDM4E (0.74) PAX8KDM4ETP53LMNAMAPT
SCHEMBL7403841 0.76 PAX8 (0.50) PAX8KDM4ETP53LMNAMAPT
SCHEMBL31243256 0.75 LOXL2 (0.60) PAX8KDM4ELMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP claimed
US-5663032-A NAPHTHOL DERIVATIVE REDUCING AGENT CANON KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0330504-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-30 EP disclosed
EP-0326424-A2 Photosensitive composition, photosensitive material, and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed