Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG2 | P78540 | 12/20 | 0.65 |
| ▸ | ARG1 | P05089 | 11/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ODC1 | P11926 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198295 | 1.00 | ARG2 (0.65) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL5322729 | 0.98 | ARG2 (0.62) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL5320097 | 0.98 | ARG2 (0.62) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL4884643 | 0.94 | ODC1 (0.64) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL4884638 | 0.94 | ODC1 (0.64) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL4884641 | 0.94 | ODC1 (0.64) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL8842963 | 0.85 | ARG2 (0.67) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL5324175 | 0.85 | MEN1 (0.65) | ARG2ARG1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL29359936 | 0.85 | ODC1 (0.63) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL264841 | 0.84 | ODC1 (0.53) | ARG2ARG1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723552-B1 | OLIGOPEPTIDES DERIVED FROM C-REACTIVE PROTEIN FRAGMENTS | ITALFARMACO SPA (IT) | 2002-10-23 | — | — | EP | claimed |
| US-6342481-B1 | RESIDUES OF THREONINE, LEUCINE, ISOLEUCINE, VALINE, SARCOSINE, ALANINE, GLYCINE AND ACYLGLYCINE | ITALFARMACO S.P.A. (IT) | 2002-01-29 | — | — | US | claimed |
| EP-3990478-A1 | TNF MUTEINS AND USES THEREOF | Oxford University Innovation Limited (GB) | 2022-05-04 | — | — | EP | disclosed |
| EP-1133309-B1 | Composition and methods for neural tissue repair | INST MEDICAL W & E HALL (AU) | 2011-10-05 | — | — | EP | disclosed |
| US-6602910-B2 | Treating cancer in a patient comprising administering an effective amount of substantially purified D enantiomer of difluoromethylornithine | ILEX ONCOLOGY, INC. | 2003-08-05 | — | — | US | disclosed |
| US-20020045663-A1 | D-enantiomer of DFMO and methods of use therefor | ILEX ONCOLOGY, INC. (US) | 2002-04-18 | — | — | US | disclosed |
| US-4339589-A | Preparation of 4-substituted oxazolidin-5-ones | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4264771-A | Alkylation of substituted oxazolinone-(5) compounds | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045663-A1 | D-enantiomer of DFMO and methods of use therefor | DHODH, DDT, HADHB | ARG2 819/4885ARG1 605/4885MEN1 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.