Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.64 |
| ▸ | ARG2 | P78540 | 11/20 | 0.61 |
| ▸ | ARG1 | P05089 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884641 | 1.00 | ODC1 (0.64) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL4884643 | 1.00 | ODC1 (0.64) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL7198295 | 0.94 | ARG2 (0.65) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL2471683 | 0.94 | ARG2 (0.65) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL5322729 | 0.92 | ARG2 (0.62) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL5320097 | 0.92 | ARG2 (0.62) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL5324175 | 0.86 | MEN1 (0.65) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL11267854 | 0.85 | ODC1 (0.62) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL11267850 | 0.85 | ODC1 (0.62) | ODC1ARG2ARG1MEN1ALDH1A1 | |
| SCHEMBL8533012 | 0.85 | ODC1 (0.62) | ODC1ARG2ARG1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8591874-B2 | Inhibition of mammalian hair growth | THE PROCTER & GAMBLE COMPANY (US) | 2013-11-26 | — | — | US | disclosed |
| US-8481015-B2 | Applying agmatine and a dermatologically acceptable carrier to the skin; inhibiting hair growth | THE PROCTER & GAMBLE COMPANY (US) | 2013-07-09 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20080188505-A1 | Regulation of Mammalian Hair Growth | OBLONG JOHN ERICH | 2008-08-07 | — | — | US | disclosed |
| US-20080057015-A1 | Hair care compositions, methods, and articles of commerce that can help maintain a longer lasting hair style appearance | THE PROCTER & GAMBLE COMPANY | 2008-03-06 | — | — | US | disclosed |
| US-20070203240-A1 | Personal care compositions and methods for regulating mammalian hair growth | THE PROCTER & GAMBLE COMPANY | 2007-08-30 | — | — | US | disclosed |
| EP-1750655-A1 | PERSONAL CARE COMPOSITIONS AND METHODS FOR REGULATING MAMMALIAN HAIR GROWTH AND SKIN CONDITION | The Procter and Gamble Company (US) | 2007-02-14 | — | — | EP | disclosed |
| US-20060127431-A1 | Regulation of mammalian hair growth | THE PROCTER & GAMBLE COMPANY | 2006-06-15 | — | — | US | disclosed |
| EP-1601340-A2 | REGULATION OF MAMMALIAN HAIR GROWTH | THE PROCTER & GAMBLE COMPANY (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2005110353-A1 | PERSONAL CARE COMPOSITIONS AND METHODS FOR REGULATING MAMMALIAN HAIR GROWTH AND SKIN CONDITION | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050255060-A1 | Personal care compositions and methods regulating mammalian hair growth | PROCTER & GAMBLE COMPANY, THE | 2005-11-17 | — | — | US | disclosed |
| US-20050255059-A1 | Personal care compositions and methods regulating mammalian hair growth | PROCTER & GAMBLE COMPANY, THE | 2005-11-17 | — | — | US | disclosed |
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-11-03 | — | — | US | disclosed |
| US-20050003024-A1 | Regulation of mammalian hair growth | THE PROCTER & GAMBLE COMPANY | 2005-01-06 | — | — | US | disclosed |
| WO-2004078157-A2 | REGULATION OF MAMMALIAN HAIR GROWTH | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255059-A1 | Personal care compositions and methods regulating mammalian hair growth | PLOD3, MITF, AADAT | ODC1 2732/4885ARG2 1235/4885ARG1 1468/4885 |
| US-20060127431-A1 | Regulation of mammalian hair growth | BHMT, UGCG, HNMT | ODC1 689/4885ARG2 1044/4885ARG1 1496/4885 |
| US-20080188505-A1 | Regulation of Mammalian Hair Growth | BHMT, UGCG, HNMT | ODC1 689/4885ARG2 1044/4885ARG1 1496/4885 |
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | SLC7A1, SRM, SLC16A1 | ODC1 15/4885ARG2 108/4885ARG1 43/4885 |
| US-20050255060-A1 | Personal care compositions and methods regulating mammalian hair growth | PCMT1, PLOD3, ARNT | ODC1 3000/4885ARG2 1364/4885ARG1 1914/4885 |
| US-20050003024-A1 | Regulation of mammalian hair growth | BHMT, UGCG, HNMT | ODC1 689/4885ARG2 1044/4885ARG1 1496/4885 |
| US-20070203240-A1 | Personal care compositions and methods for regulating mammalian hair growth | PLOD1, PLOD3, PLOD2 | ODC1 242/4885ARG2 747/4885ARG1 998/4885 |
| US-20080057015-A1 | Hair care compositions, methods, and articles of commerce that can help maintain a longer lasting hair style appearance | SHH, CAPRIN1, CUTA | ODC1 1974/4885ARG2 2308/4885ARG1 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.