SCHEMBL24717451

SCHEMBL24717451

Cc1c(F)cc2c(c1F)CCC(O)C2

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.33
DRD3 P35462 6/20 0.33
HTR1A P08908 4/20 0.33
HTR7 P34969 4/20 0.33
CYP1A2 P05177 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12976105 0.81 ALDH1A1 (0.38) DRD2DRD3HTR1AHTR7
SCHEMBL29306482 0.80 DRD2 (0.54) DRD2DRD3
SCHEMBL25828868 0.74 NOTUM (0.33)
SCHEMBL3424340 0.74 TRPV1 (0.36) DRD2DRD3HTR1AHTR7CYP1A2
SCHEMBL4372391 0.74 TRPV1 (0.36) DRD2DRD3HTR1AHTR7CYP1A2
SCHEMBL29365669 0.74 TRPV1 (0.36) DRD2DRD3HTR1AHTR7CYP1A2
SCHEMBL6952511 0.74 TRPV1 (0.36) DRD2DRD3HTR1AHTR7CYP1A2
SCHEMBL29365060 0.74 TRPV1 (0.36) DRD2DRD3HTR1AHTR7CYP1A2
SCHEMBL27431533 0.72 UGT2B17 (0.42) CYP11B1CYP11B2
SCHEMBL6948524 0.72 CYP1A2 (0.41) DRD2DRD3CYP1A2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
WO-2022234709-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE AND ANTENNA EACH USING SAME DIC株式会社 2022-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME TTI2, CCT4, CCT2 DRD2 1768/4885DRD3 2110/4885HTR1A 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.