Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16546534 | 0.87 | MEN1 (0.35) | — | |
| SCHEMBL12976105 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL24717451 | 0.74 | DRD2 (0.33) | — | |
| SCHEMBL29306482 | 0.74 | DRD2 (0.54) | — | |
| SCHEMBL25827151 | 0.72 | — | — | |
| SCHEMBL18315092 | 0.72 | KLKB1 (0.31) | — | |
| SCHEMBL13218784 | 0.71 | — | — | |
| SCHEMBL21892900 | 0.69 | DRD2 (0.31) | — | |
| SCHEMBL11415512 | 0.68 | HDAC1 (0.37) | — | |
| SCHEMBL2044065 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125841-A1 | HETEROCYCLIC COMPOUND AS POLθ INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-07-06 | — | — | WO | disclosed |