Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24689480 | 0.96 | ADRA1B (0.58) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL24719040 | 0.89 | TSHR (0.61) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL3844518 | 0.87 | DRD2 (0.54) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL24719242 | 0.87 | DRD2 (0.59) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL4502971 | 0.86 | DRD2 (0.65) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL22302984 | 0.84 | MEN1 (0.59) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL24720694 | 0.84 | DRD2 (0.54) | DRD2DRD3HTR1A | |
| SCHEMBL3863328 | 0.81 | DRD2 (0.57) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL4502968 | 0.81 | DRD2 (0.59) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL3436476 | 0.81 | ADRA1B (0.51) | ADRA1BADRA1DADRA1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056568-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-09-14 | — | — | EP | disclosed |