Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302984 | 0.96 | MEN1 (0.59) | TSHRLMNAMAPK1NPC1ALOX15 | |
| SCHEMBL24720737 | 0.89 | ADRA1B (0.56) | TSHRDRD2DRD3HTR1AADRA1D | |
| SCHEMBL22302847 | 0.87 | ALDH1A1 (0.55) | TSHRLMNAMAPK1NPC1ALOX15 | |
| SCHEMBL24719242 | 0.87 | DRD2 (0.59) | DRD2HTR2AHTR2CSLC6A4DRD3 | |
| SCHEMBL13698454 | 0.86 | TSHR (0.63) | TSHRLMNAMAPK1NPC1ALOX15 | |
| SCHEMBL22302839 | 0.85 | ALDH1A1 (0.53) | TSHRLMNAMAPK1NPC1ALOX15 | |
| SCHEMBL24689480 | 0.85 | ADRA1B (0.58) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL25106918 | 0.84 | ALDH1A1 (0.58) | TSHRLMNAMAPK1NPC1ALOX15 | |
| SCHEMBL3845063 | 0.84 | ALDH1A1 (0.52) | TSHRLMNAMAPK1NPC1ALOX15 | |
| SCHEMBL22302302 | 0.83 | TSHR (0.47) | TSHRLMNAMAPK1NPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150068-A2 | DOPAMINE D3/D2 RECEPTOR MODULATING COMPOUNDS | RICHTER GEDEON NYRT. (HU) | 2024-07-18 | — | — | WO | disclosed |
| EP-4056568-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-09-14 | — | — | EP | disclosed |