Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722687 | 0.80 | CRBN (0.34) | DRD2DRD1CRBN | |
| SCHEMBL24723535 | 0.80 | SMYD3 (0.36) | SMYD3DRD2DRD1CRBNPOLB | |
| SCHEMBL24722688 | 0.78 | CRBN (0.33) | DRD2DRD1CRBN | |
| SCHEMBL6368447 | 0.72 | CRBN (0.51) | CRBNCHEK1AURKADAPK3PRKD3 | |
| SCHEMBL25704837 | 0.72 | TSHR (0.38) | CRBNALDH1A1HTTDDB1 | |
| SCHEMBL6466846 | 0.72 | NNMT (0.39) | SMYD3CRBNCHEK1AURKADAPK3 | |
| SCHEMBL728499 | 0.71 | ABL1 (0.58) | SMYD3CRBNCHEK1AURKADAPK3 | |
| SCHEMBL24722682 | 0.70 | CRBN (0.43) | CRBNCHEK1AURKADAPK3PRKD3 | |
| SCHEMBL24822956 | 0.69 | CRBN (0.31) | SMYD3CRBNDDB1 | |
| SCHEMBL24722680 | 0.69 | NNMT (0.32) | SMYD3CHEK1AURKADAPK3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187329-A1 | FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-09-09 | — | — | WO | disclosed |