Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466846 | 0.74 | NNMT (0.39) | NNMTSMYD3CRBN | |
| SCHEMBL24723535 | 0.68 | SMYD3 (0.36) | NNMTSMYD3DDB1CRBN | |
| SCHEMBL13564023 | 0.66 | ACHE (0.40) | NNMT | |
| SCHEMBL21366374 | 0.66 | NNMT (0.33) | NNMT | |
| SCHEMBL15541609 | 0.64 | SMYD3 (0.39) | NNMTSMYD3CRBN | |
| SCHEMBL24722714 | 0.64 | AKR1B1 (0.34) | NNMTDDB1CRBN | |
| SCHEMBL21358706 | 0.64 | SMYD3 (0.36) | NNMTSMYD3 | |
| SCHEMBL22900729 | 0.64 | NNMT (0.34) | NNMT | |
| SCHEMBL728499 | 0.64 | ABL1 (0.58) | SMYD3CRBN | |
| SCHEMBL24722687 | 0.63 | CRBN (0.34) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187329-A1 | FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-09-09 | — | — | WO | disclosed |