Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 8/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722961 | 0.81 | CHRM4 (0.31) | CHRM4PDE2A | |
| SCHEMBL24723080 | 0.80 | NOS3 (0.35) | DAOCHRM4PIK3CACSF1R | |
| SCHEMBL24722863 | 0.80 | DAO (0.33) | DAOCHRM4PDE2ACSF1R | |
| SCHEMBL24723066 | 0.79 | ALOX15 (0.36) | — | |
| SCHEMBL24723271 | 0.72 | DAO (0.36) | DAOCHRM4 | |
| SCHEMBL24157002 | 0.71 | DAO (0.35) | DAOPIK3CACCNCCDK8 | |
| SCHEMBL25928325 | 0.70 | — | — | |
| SCHEMBL24723084 | 0.69 | DAO (0.34) | DAOCHRM4 | |
| SCHEMBL24722919 | 0.69 | DAO (0.34) | DAOCHRM4CSF1R | |
| SCHEMBL24683585 | 0.67 | ERN1 (0.34) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |