Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516933 | 0.67 | TDP1 (0.30) | — | |
| SCHEMBL30068766 | 0.67 | CHEK1 (0.39) | — | |
| SCHEMBL24683601 | 0.67 | CHEK1 (0.39) | — | |
| SCHEMBL25257054 | 0.67 | MET (0.33) | — | |
| SCHEMBL19244018 | 0.67 | ADORA2A (0.34) | — | |
| SCHEMBL24342279 | 0.65 | KDM4E (0.44) | LMNA | |
| SCHEMBL7513614 | 0.65 | CHEK1 (0.45) | LMNA | |
| SCHEMBL23581024 | 0.64 | GABRP (0.54) | LMNA | |
| SCHEMBL30178553 | 0.64 | GABRP (0.54) | LMNA | |
| SCHEMBL30994421 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |