SCHEMBL24723409

SCHEMBL24723409

CC(=O)Oc1ccc2[nH]cc(Br)c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 4/20 0.59
HTR1B P28222 3/20 0.47
HTR1A P08908 2/20 0.47
KDM4E B2RXH2 3/20 0.47
SLC22A6 Q4U2R8 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA2 P00918 1/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
NR4A2 P43354 1/20 0.46
MEN1 O00255 2/20 0.45
RAB9A P51151 2/20 0.45
KMT2A Q03164 2/20 0.45
MTNR1A P48039 2/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP1A1 P04798 1/20 0.45
MPO P05164 1/20 0.45
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL27585993 0.87 HTR1D (0.51) HTR1DHTR1BHTR1AKDM4ECYP1A2
SCHEMBL27693186 0.83 HTR1D (0.60) HTR1DHTR1BHTR1AKDM4ESLC22A6
SCHEMBL29055670 0.81 TUBB4A (0.50) HTR1DHTR1BHTR1ACYP1A2CYP2C19
SCHEMBL27502387 0.79 ALDH1A1 (0.68) HTR1DHTR1BHTR1AKDM4ESLC22A6
SCHEMBL4475932 0.78 GPR84 (0.62) HTR1DHTR1BHTR1AKDM4ECYP1A2
SCHEMBL10413233 0.77 HTR1D (0.76) HTR1DHTR1BHTR1AKDM4ECYP1A2
SCHEMBL12720798 0.77 CYP1A2 (0.76) HTR1DHTR1BHTR1ACYP1A2CYP2C9
SCHEMBL11188479 0.77 HTR1D (0.54) HTR1DHTR1BHTR1AKDM4ECYP1A2
SCHEMBL9828421 0.76 HTR1D (0.67) HTR1DHTR1BHTR1AKDM4ECYP1A2
SCHEMBL8304643 0.76 HTR1D (0.50) HTR1DHTR1BHTR1AKDM4ECA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022232931-A1 CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS KARE CHEMICAL TECHNOLOGIES INC. (CA) 2022-11-10 WO disclosed