Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20020392 | 0.70 | KMT2A (0.56) | NPBWR1MCHR1MAPK1KMT2AMEN1 | |
| SCHEMBL12092549 | 0.69 | MEN1 (0.46) | NPBWR1MCHR1MAPK1KMT2AMEN1 | |
| SCHEMBL6211759 | 0.66 | MEN1 (0.55) | NPBWR1MCHR1MAPK1KMT2AMEN1 | |
| SCHEMBL20320324 | 0.65 | NPBWR1 (0.42) | NPBWR1MCHR1KMT2AMEN1KDM4E | |
| SCHEMBL14300869 | 0.65 | MAPK1 (0.42) | MAPK1KMT2AMEN1PYCR1KDM4E | |
| SCHEMBL13039136 | 0.63 | KDM4E (0.61) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL3407812 | 0.63 | KDM4E (0.61) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL21340480 | 0.63 | KDM4E (0.61) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL15308458 | 0.63 | DRD2 (0.44) | NPBWR1MCHR1MAPK1KMT2AMEN1 | |
| SCHEMBL18995687 | 0.63 | MAOB (0.56) | MAPK1PYCR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220235082-A1 | CATALYSTS | THE UNIVERSITY OF WARWICK (GB) | 2022-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220235082-A1 | CATALYSTS | TST, TCP1, CCT3 | NPBWR1 4218/4885MCHR1 4661/4885MAPK1 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.