Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003361 | 1.00 | KDM4E (0.35) | KDM4EPOLBGAARAF1HCRTR1 | |
| SCHEMBL29947388 | 0.76 | KDM4E (0.37) | KDM4EPOLBGAAHPGDMAPT | |
| SCHEMBL26981246 | 0.76 | KDM4E (0.37) | KDM4EPOLBGAAHPGDMAPT | |
| SCHEMBL12068861 | 0.75 | POLB (0.32) | POLBL3MBTL1 | |
| SCHEMBL10253926 | 0.75 | POLB (0.32) | POLBL3MBTL1 | |
| SCHEMBL3302582 | 0.75 | DGAT1 (0.44) | KDM4EPOLBNPC1HPGDMAPT | |
| SCHEMBL18281305 | 0.74 | MAPK1 (0.36) | KDM4EPOLBGAAHPGDMAPT | |
| SCHEMBL22481338 | 0.73 | P2RX7 (0.49) | POLBHPGDMAPTKMT2AALDH1A1 | |
| SCHEMBL14906735 | 0.73 | NPC1 (0.47) | KDM4EPOLBNPC1TSHRHPGD | |
| SCHEMBL14683911 | 0.71 | CNR1 (0.40) | KDM4EPOLBNPC1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253259-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |