Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428907 | 0.81 | HPGD (0.56) | KMT2AALDH1A1MAPTESR1ESR2 | |
| SCHEMBL25248 | 0.77 | NPC1 (0.43) | KMT2AMAPTCYP1A2CYP2C19CES2 | |
| SCHEMBL23289 | 0.75 | F2 (0.48) | KMT2AALDH1A1MAPTESR1ESR2 | |
| SCHEMBL3231544 | 0.75 | F2 (0.30) | LMNA | |
| SCHEMBL9620982 | 0.75 | SLC6A3 (0.59) | KMT2AALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL3428268 | 0.75 | ESR1 (0.43) | KMT2AALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL8585925 | 0.75 | KMT2A (0.52) | KMT2AALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL5687713 | 0.75 | KMT2A (0.60) | KMT2AALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL23380 | 0.73 | ESR1 (0.52) | KMT2AALDH1A1MAPTCES2CES1 | |
| SCHEMBL8226022 | 0.73 | CYP3A4 (0.40) | KMT2AALDH1A1MAPTCYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | claimed |
| US-9006266-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | claimed |
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | disclosed |
| EP-2609094-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-9930890-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-04-03 | — | — | US | disclosed |
| US-20180007903-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-01-11 | — | — | US | disclosed |
| EP-3241829-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-9770027-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2017-09-26 | — | — | US | disclosed |
| EP-3109248-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2016-12-28 | — | — | EP | disclosed |
| US-20160309719-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH | 2016-10-27 | — | — | US | disclosed |
| US-9434723-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| US-9150565-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20150175598-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | US | disclosed |
| US-9006266-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-07-24 | — | — | US | disclosed |
| US-8759527-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-24 | — | — | US | disclosed |
| US-20130296272-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
| EP-2609094-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2012025557-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175598-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | KMT2A 1254/4885ALDH1A1 1292/4885MAPT 3865/4885 |
| US-20180007903-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | KMT2A 1254/4885ALDH1A1 1292/4885MAPT 3865/4885 |
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | KMT2A 1254/4885ALDH1A1 1292/4885MAPT 3865/4885 |
| US-20160309719-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | KMT2A 1254/4885ALDH1A1 1292/4885MAPT 3865/4885 |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | KMT2A 1254/4885ALDH1A1 1292/4885MAPT 3865/4885 |
| US-20130296272-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | KMT2A 1254/4885ALDH1A1 1292/4885MAPT 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.