Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23289 | 0.87 | F2 (0.48) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL28263594 | 0.79 | HSD17B10 (0.72) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL25248 | 0.78 | NPC1 (0.43) | SLC6A3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4386437 | 0.78 | ALDH1A1 (0.73) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL3428907 | 0.76 | HPGD (0.56) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL1914132 | 0.76 | SLC6A3 (0.72) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL6948356 | 0.76 | SLC6A3 (0.72) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL113040 | 0.76 | SLC6A3 (0.71) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL30505635 | 0.76 | SLC6A3 (0.71) | SLC6A3ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL1979275 | 0.76 | SLC6A3 (0.71) | SLC6A3ALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321504-B1 | CHIRAL ARYLOXY PROPIONIC ACID ESTERS AND THEIR USE AS DOPING AGENT IN LIQUID CRYSTAL PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | claimed |
| US-4985172-A | CONVERT SMECTIIC INTO FERROELECTRIC LIQUID CRYSTALS | HOECHST AG (DE) | 1991-01-15 | — | — | US | disclosed |