Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160730 | 0.92 | L3MBTL1 (0.47) | NPC1TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12160900 | 0.92 | L3MBTL1 (0.47) | NPC1TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26878431 | 0.88 | LMNA (0.48) | NPC1RAB9AALDH1A1NAMPTPOLB | |
| SCHEMBL26899136 | 0.88 | NPC1 (0.46) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL25083897 | 0.88 | LMNA (0.48) | NPC1RAB9AALDH1A1NAMPTPOLB | |
| SCHEMBL12160727 | 0.81 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL12160901 | 0.81 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL12176425 | 0.81 | KMT2A (0.58) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL15088272 | 0.80 | ALDH1A1 (0.48) | TP53TSHRALDH1A1GAAKMT2A | |
| SCHEMBL25083896 | 0.79 | POLB (0.48) | TSHRSMN1; SMN2ALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |