SCHEMBL24726527

SCHEMBL24726527

CC(C)c1cccc(C#Cc2cccc(F)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
CA1 P00915 2/20 0.47
GRM5 P41594 7/20 0.46
SLC6A2 P23975 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179253 0.82 ACHE (0.48) CA2CA9CA1
SCHEMBL9302636 0.82 CA12 (0.62) CA12CA2CA9CA1GRM5
SCHEMBL31286312 0.82 CA12 (0.62) CA12CA2CA9CA1GRM5
Ethylene SCHEMBL27799285 0.78 ACHE (0.44) CA2CA9CA1
SCHEMBL13647259 0.77 CA12 (0.46) CA12CA2CA9CA1GRM5
Methoxymethane SCHEMBL28044286 0.76 AOC3 (0.49) CA2CA9CA1
SCHEMBL717450 0.76 CA12 (0.59) CA12CA2CA9CA1GRM5
SCHEMBL4371227 0.76 CA12 (0.49) CA12CA2CA9CA1GRM5
SCHEMBL13119197 0.75 TAAR1 (0.53) CA2CA9CA1
SCHEMBL9304700 0.74 CA12 (0.62) CA12CA2CA9CA1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022234965-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 보로노이 2022-11-10 WO disclosed