Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.78 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.78 |
| ▸ | BRD2 | P25440 | 5/20 | 0.78 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888610 | 0.88 | BRD4 (0.74) | BRD4CREBBPBRD2BRD3NPC1 | |
| SCHEMBL14196935 | 0.80 | BRD4 (0.61) | BRD4CREBBPBRD2BRD3 | |
| SCHEMBL12487 | 0.80 | NPC1 (0.69) | BRD4CREBBPBRD2BRD3NPC1 | |
| SCHEMBL16246450 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2BRD3NPC1 | |
| SCHEMBL9657290 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2BRD3NPC1 | |
| SCHEMBL980536 | 0.77 | MAP4K4 (0.76) | BRD4CREBBPBRD2BRD3NPC1 | |
| SCHEMBL16404612 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2BRD3NPC1 | |
| SCHEMBL7453671 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2BRD3 | |
| SCHEMBL15980858 | 0.76 | BRD4 (0.68) | BRD4CREBBPBRD2 | |
| SCHEMBL19754248 | 0.76 | BRD4 (0.67) | BRD4CREBBPBRD2BRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |