Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781978 | 1.00 | MAPK1 (0.46) | MAPK1NAMPTDDB1CRBNTAOK3 | |
| SCHEMBL30880400 | 0.81 | SLC6A2 (0.42) | NAMPTSLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL30054994 | 0.79 | USP30 (0.40) | NAMPTGPR119USP30RORCIDO1 | |
| SCHEMBL24726442 | 0.79 | USP30 (0.40) | NAMPTGPR119USP30RORCIDO1 | |
| SCHEMBL31568339 | 0.78 | RBP4 (0.37) | NAMPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27393732 | 0.77 | NAMPT (0.51) | NAMPT | |
| SCHEMBL31568342 | 0.77 | NR2E1 (0.43) | NAMPTSLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL31710983 | 0.77 | SCD5 (0.39) | MAPK1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL27392450 | 0.76 | ALDH1A1 (0.39) | MAPK1NAMPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31710803 | 0.76 | SLC6A2 (0.37) | NAMPTABHD6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396073-A | Microbiocidal tetrahydroisoquinoline derivatives | 先正达农作物保护股份公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022253645-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-08 | — | — | WO | disclosed |