SCHEMBL24726844

SCHEMBL24726844

CC(=O)CN(C(=O)OC(C)(C)C)C(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
MTOR P42345 1/20 0.39
CTSK P43235 3/20 0.39
RIPK1 Q13546 2/20 0.38
CASR P41180 1/20 0.38
CTSS P25774 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
MAPT P10636 1/20 0.36
GPR88 Q9GZN0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20741092 0.90 DAGLA (0.41) ALOX5MTORCTSKRIPK1CASR
SCHEMBL20741091 0.90 DAGLA (0.41) ALOX5MTORCTSKRIPK1CASR
SCHEMBL20741070 0.86 CASR (0.41) ALOX5MTORCTSKCASRCTSS
SCHEMBL20741069 0.86 CASR (0.41) ALOX5MTORCTSKCASRCTSS
SCHEMBL957546 0.86 L3MBTL1 (0.39) ALOX5MTORCTSKRIPK1CASR
SCHEMBL957545 0.86 L3MBTL1 (0.39) ALOX5MTORCTSKRIPK1CASR
SCHEMBL20741072 0.85 MTOR (0.40) ALOX5MTORCTSKCTSS
SCHEMBL20741073 0.85 MTOR (0.40) ALOX5MTORCTSKCTSS
SCHEMBL1222928 0.82 PTGS2 (0.42) CTSKCTSSMAPT
SCHEMBL14067608 0.81 GPR88 (0.45) ALOX5MTORCTSKRIPK1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626232-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2025-10-08 EP disclosed
WO-2024115546-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 WO disclosed
WO-2024115546-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 WO disclosed
EP-4346411-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-04-10 EP disclosed
CN-117396073-A Microbiocidal tetrahydroisoquinoline derivatives 先正达农作物保护股份公司 2024-01-12 CN disclosed
WO-2022253645-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 WO disclosed
WO-2022253645-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 WO disclosed