SCHEMBL24727871

SCHEMBL24727871

C=C(C)C(=O)Oc1nc(C)nc(N)n1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.33
▸ HSP90AB1 P08238 1/20 0.32
▸ ELANE P08246 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24322121 0.89 LMNA (0.48) LMNAALDH1A1ELANEKDM4ECYP1A2
SCHEMBL26203638 0.81 ALDH1A1 (0.34) ALDH1A1ELANE
SCHEMBL28822152 0.80 LMNA (0.40) LMNAALDH1A1ELANE
SCHEMBL21344978 0.79 ALDH1A1 (0.33) ALDH1A1ELANE
SCHEMBL24728016 0.79 ALDH1A1 (0.33) ALDH1A1ELANE
SCHEMBL10529247 0.79 ALDH1A1 (0.46) LMNAALDH1A1ELANE
SCHEMBL27828107 0.79 LMNA (0.35) LMNAALDH1A1CYP1A2
SCHEMBL24728019 0.78 ELANE (0.34) ALDH1A1ELANE
SCHEMBL718955 0.76 LMNA (0.33) LMNACYP1A2
SCHEMBL24727878 0.76 THRB (0.33) LMNAHSP90AB1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295457-A1 SURFACE TREATMENT LIQUID AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-21 — — US disclosed
US-20230295457-A1 SURFACE TREATMENT LIQUID AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-21 — — US disclosed
US-20230272143-A1 SURFACE TREATMENT LIQUID AND HYDROPHILIZING TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-08-31 — — US disclosed
US-20230272143-A1 SURFACE TREATMENT LIQUID AND HYDROPHILIZING TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-08-31 — — US disclosed
US-20220267495-A1 POLYMERIZABLE COMPOSITION AND HYDROPHILIZING TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2022-08-25 — — US disclosed
Send feedback