Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689083 | 0.84 | MAPT (0.59) | C5AR1MAOBMAPTMAPK1ALDH1A1 | |
| SCHEMBL3915606 | 0.81 | MAOB (0.58) | MAOBABCB1HTR1ADRD2MAPT | |
| SCHEMBL30189780 | 0.81 | MAOB (0.58) | MAOBABCB1HTR1ADRD2MAPT | |
| SCHEMBL9315251 | 0.81 | MAOB (0.58) | MAOBABCB1HTR1ADRD2MAPT | |
| SCHEMBL18487331 | 0.80 | C5AR1 (0.47) | C5AR1MAOBCTSLCTSBABCB1 | |
| SCHEMBL1026336 | 0.79 | MAOB (0.54) | C5AR1MAOBABCB1HTR1ADRD2 | |
| SCHEMBL12772071 | 0.77 | MAOB (0.62) | MAOBABCB1HTR1ADRD2KDM4E | |
| SCHEMBL13791570 | 0.77 | MAOB (0.62) | MAOBABCB1HTR1ADRD2MAPT | |
| SCHEMBL3781528 | 0.76 | APP (0.47) | MAOBMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL3793161 | 0.76 | GSTP1 (0.57) | MAOBMAPTMAPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473264-B2 | Inhibitors of erythrocyte band 3 tyrosine phosphorylation and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2025-11-18 | — | — | US | disclosed |
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2022-12-08 | — | — | US | disclosed |
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | SPTBN1, CTTN, HBG1 | C5AR1 4080/4885MAOB 3013/4885CTSL 3933/4885 |
| US-12473264-B2 | Inhibitors of erythrocyte band 3 tyrosine phosphorylation and uses thereof | HBG1, SPTBN1, CTTN | C5AR1 2818/4885MAOB 2588/4885CTSL 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.