Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6361103 | 0.85 | PDGFRB (0.47) | HTR1AMAPTGAAADRA1DADRA1A | |
| SCHEMBL2873708 | 0.81 | MAOB (0.62) | MAOBC5AR1ABCB1HTR1ADRD2 | |
| SCHEMBL1031014 | 0.80 | PTGES (0.49) | MAOBC5AR1ABCB1HTR1ADRD2 | |
| SCHEMBL24728131 | 0.79 | C5AR1 (0.48) | MAOBC5AR1ABCB1HTR1ADRD2 | |
| SCHEMBL31757025 | 0.78 | CHRNA7 (0.51) | HTR1AHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2006949 | 0.78 | MAOB (0.56) | MAOBC5AR1ABCB1HTR1ADRD2 | |
| SCHEMBL11223475 | 0.76 | NPC1 (0.51) | MAOBABCB1HTR1AMAPTHPGD | |
| SCHEMBL8267913 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL21070386 | 0.76 | CHRNA7 (0.49) | HTR1AMAPTHPGDSMN1; SMN2ADRA1D | |
| SCHEMBL31664070 | 0.76 | CHRNA7 (0.49) | HTR1AMAPTHPGDSMN1; SMN2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150527-B1 | ANTHRANILIC ACID DERIVATIVE AS ANTICANCER AGENT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2011-01-19 | — | — | EP | claimed |
| EP-2150527-B1 | ANTHRANILIC ACID DERIVATIVE AS ANTICANCER AGENT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2011-01-19 | — | — | EP | disclosed |