Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434617 | 0.86 | MRGPRX4 (0.48) | C5AR1MAOBMRGPRX4MAPTFFAR1 | |
| SCHEMBL9315251 | 0.81 | MAOB (0.58) | MAOBMRGPRX4MAPTABCB1HTR1A | |
| SCHEMBL689377 | 0.81 | MAPT (0.46) | MRGPRX4MAPTFFAR1MAPK1ABCB1 | |
| Hydrochloric Acid SCHEMBL27830190 | 0.80 | MAOB (0.57) | MAOBMRGPRX4MAPTMAPK1FFAR4 | |
| SCHEMBL24728131 | 0.80 | C5AR1 (0.48) | C5AR1MAOBMAPTNPSR1MAPK1 | |
| SCHEMBL3915606 | 0.76 | MAOB (0.58) | MAOBMAPTABCB1HTR1ADRD2 | |
| SCHEMBL30189780 | 0.76 | MAOB (0.58) | MAOBMAPTABCB1HTR1ADRD2 | |
| SCHEMBL12667384 | 0.74 | MRGPRX4 (0.60) | MRGPRX4MAPTFFAR1MAPK1FFAR4 | |
| SCHEMBL3790941 | 0.74 | MAPT (0.58) | MAOBMAPTNPSR1MAPK1 | |
| SCHEMBL1026336 | 0.74 | MAOB (0.54) | C5AR1MAOBMAPTMAPK1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247751-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2020-08-06 | — | — | US | disclosed |
| US-20190077755-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2019-03-14 | — | — | US | disclosed |
| US-10173978-B2 | Small molecule androgen receptor inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180215712-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2018-08-02 | — | — | US | disclosed |
| WO-2017023916-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2017-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215712-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | AR, KLK3, BRDT | C5AR1 2796/4885MAOB 2809/4885MRGPRX4 2885/4885 |
| US-20190077755-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | AR, KLK3, BRDT | C5AR1 2796/4885MAOB 2809/4885MRGPRX4 2885/4885 |
| US-20200247751-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | AR, KLK3, BRDT | C5AR1 2796/4885MAOB 2809/4885MRGPRX4 2885/4885 |
| US-10173978-B2 | Small molecule androgen receptor inhibitors and methods of use thereof | AR, KLK3, BRDT | C5AR1 2796/4885MAOB 2809/4885MRGPRX4 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.