SCHEMBL24728283

SCHEMBL24728283

CC1(C)C=Cc2c(ccc3cc(C(=O)/C=C/c4ccc[nH]4)oc23)O1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.41
ODC1 P11926 2/20 0.41
ACHE P22303 2/20 0.41
BCHE P06276 1/20 0.41
BACE1 P56817 1/20 0.41
HIF1AN Q9NWT6 1/20 0.41
MAPT P10636 3/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
PDE4D Q08499 1/20 0.39
HTT P42858 1/20 0.39
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728235 0.84 PTPN1 (0.40) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL29822730 0.84 PTPN1 (0.40) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL24728166 0.83 PTPN1 (0.52) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL24728230 0.81 MAPT (0.45) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL29822690 0.79 PTPN1 (0.42) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL29823031 0.78 HIF1AN (0.50) ODC1ACHEBCHEHIF1ANMAPT
SCHEMBL24728221 0.78 HIF1AN (0.50) ODC1ACHEBCHEHIF1ANMAPT
SCHEMBL24728220 0.78 PDE4D (0.46) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL24728239 0.78 ACHE (0.55) PTPN1ODC1ACHEBCHEBACE1
SCHEMBL24728324 0.78 ACHE (0.66) PTPN1ODC1ACHEBCHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022158624-A1 NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME 연세대학교 산학협력단 2022-07-28 WO claimed
WO-2022158624-A1 NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME 연세대학교 산학협력단 2022-07-28 WO disclosed
WO-2022158624-A1 NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME 연세대학교 산학협력단 2022-07-28 WO disclosed