SCHEMBL24728697

SCHEMBL24728697

Cc1ccc(C(=O)c2cc3ccc4c(c3o2)C=CC(C)(C)O4)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.47
NPC1 O15118 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
PDE4D Q08499 4/20 0.45
HTT P42858 1/20 0.42
PTPN1 P18031 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSP90AA1 P07900 3/20 0.39
XDH P47989 1/20 0.38
HIF1A Q16665 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728163 0.90 RAB9A (0.52) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL24728160 0.89 PDE4D (0.44) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL29822611 0.89 PDE4D (0.44) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL24728286 0.83 PDE4D (0.50) ALDH1A1HPGDPDE4DPTPN1HSP90AA1
SCHEMBL24728220 0.79 PDE4D (0.46) PDE4DPTPN1HSP90AA1XDHHIF1A
SCHEMBL24728166 0.74 PTPN1 (0.52) SMN1; SMN2ALDH1A1MAPTHPGDPTPN1
SCHEMBL24728230 0.71 MAPT (0.45) RAB9ANPC1ALDH1A1MAPTHPGD
SCHEMBL29822690 0.71 PTPN1 (0.42) ALDH1A1MAPTPDE4DPTPN1XDH
SCHEMBL24728304 0.71 PDE4D (0.48) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL24728324 0.71 ACHE (0.66) RAB9ANPC1ALDH1A1MAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022158624-A1 NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME 연세대학교 산학협력단 2022-07-28 WO disclosed