SCHEMBL2472846

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2500894	0.95	HDAC1 (0.53)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3835566	0.92	SMN1; SMN2 (0.49)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3836379	0.91	HDAC1 (0.50)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3829651	0.90	HDAC1 (0.47)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL2474631	0.90	HDAC1 (0.50)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3835487	0.89	HDAC1 (0.47)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3835948	0.89	HDAC1 (0.54)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3834609	0.88	KMT2A (0.49)	HDAC1HDAC2HDAC6HDAC3HDAC4
	SCHEMBL3832635	0.86	MAPT (0.51)	HDAC1TP53GAAHTTALDH1A1
	SCHEMBL13591364	0.86	NPC1 (0.41)	HDAC1HDAC2HDAC6HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.