SCHEMBL24728554

SCHEMBL24728554

NNc1cc(F)cc(CO)c1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
IDO1 P14902 4/20 0.39
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
ACHE P22303 1/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
GAA P10253 1/20 0.32
TOP2A P11388 1/20 0.30
TOP2B Q02880 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108535 0.77 CYP4F2 (0.52) CYP4F2CYP4A11IDO1CHRNB4CHRNA3
SCHEMBL16959483 0.77 CYP4F2 (0.52) CYP4F2CYP4A11IDO1CHRNB4CHRNA3
SCHEMBL2075947 0.77 CA12 (0.45) IDO1CA12CA1CA9GAA
Hydrochloric Acid SCHEMBL718965 0.74 CA12 (0.43) IDO1CA12CA1CA9GAA
SCHEMBL16555721 0.73 ACHE (0.67) CYP4F2CYP4A11IDO1CHRNB4CHRNA3
SCHEMBL17064613 0.71 CYP4F2 (0.44) CYP4F2CYP4A11IDO1CHRNB4CHRNA3
SCHEMBL26707682 0.69 CYP4F2 (0.46) CYP4F2CYP4A11IDO1CHRNB4CHRNA3
SCHEMBL4354231 0.68 TOP2A (0.47) IDO1TOP2ATOP2B
SCHEMBL360242 0.67 RAPGEF4 (0.48) IDO1
SCHEMBL16681079 0.67 CYP4F2 (0.44) CYP4F2CYP4A11IDO1CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023061457-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF 百奥泰生物制药股份有限公司 2023-04-20 WO disclosed
WO-2022253284-A1 DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2022-12-08 WO disclosed