Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729120 | 1.00 | DNM1 (0.44) | DNM1KDM5APHF8DGKAKDM4C | |
| SCHEMBL31721549 | 1.00 | DNM1 (0.44) | DNM1KDM5APHF8DGKAKDM4C | |
| SCHEMBL29255825 | 0.94 | KDM5A (0.49) | KDM5APHF8KDM4CMAPTMEN1 | |
| SCHEMBL25288794 | 0.94 | DNM1 (0.44) | DNM1KDM5APHF8DGKAKDM4C | |
| SCHEMBL31721661 | 0.94 | DNM1 (0.44) | DNM1KDM5APHF8DGKAKDM4C | |
| SCHEMBL25364226 | 0.94 | DNM1 (0.44) | DNM1KDM5APHF8DGKAKDM4C | |
| SCHEMBL25691548 | 0.92 | DGKA (0.51) | DNM1DGKALMNAPAMKDM4E | |
| SCHEMBL24728573 | 0.90 | DNM1 (0.46) | DNM1KDM5APHF8DGKAKDM4C | |
| SCHEMBL19715022 | 0.90 | DGKA (0.52) | DNM1DGKAMAPTMAPK1LMNA | |
| SCHEMBL20836044 | 0.90 | DGKA (0.52) | DNM1DGKAMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288104-A1 | LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY | Ramot at Tel-Aviv University Ltd. (IL) | 2023-12-13 | — | — | EP | disclosed |
| CN-117136074-A | Lipids suitable for nucleic acid delivery | 雷蒙特亚特特拉维夫大学有限公司 | 2023-11-28 | — | — | CN | disclosed |
| WO-2022168085-A1 | LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022168085-A1 | LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-08-11 | — | — | WO | disclosed |