SCHEMBL24728573

SCHEMBL24728573

CCCCCCCCCCCCN(CCC)CCCCCCCCCC(=O)ON(CCCCCCCCCC)CCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.46
DGKA P23743 1/20 0.46
KDM5A P29375 4/20 0.45
PHF8 Q9UPP1 2/20 0.45
KDM4C Q9H3R0 1/20 0.45
LMNA P02545 3/20 0.43
PAM P19021 2/20 0.42
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
TSHR P16473 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
ICMT O60725 1/20 0.39
ALB P02768 1/20 0.39
ALDH1A1 P00352 1/20 0.39
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28657236 0.91 DGKA (0.53) DNM1DGKALMNAPAMMAPT
SCHEMBL25288794 0.90 DNM1 (0.44) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL31721549 0.90 DNM1 (0.44) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL24729120 0.90 DNM1 (0.44) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL24728694 0.90 DNM1 (0.44) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL31721661 0.90 DNM1 (0.44) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL24728760 0.90 DNM1 (0.46) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL24728719 0.89 DNM1 (0.43) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL24728778 0.89 DNM1 (0.43) DNM1DGKAKDM5APHF8KDM4C
SCHEMBL25244397 0.88 DNM1 (0.47) DNM1DGKAKDM5APHF8KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022168085-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-08-11 WO disclosed