Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864575 | 0.85 | HTR6 (0.40) | L3MBTL1ACHEBRD4CREBBPKMT2A | |
| SCHEMBL999150 | 0.79 | L3MBTL1 (0.48) | L3MBTL1ACHEBRD4CREBBPKMT2A | |
| SCHEMBL30912193 | 0.77 | L3MBTL1 (0.50) | L3MBTL1ACHEBRD4CREBBPKMT2A | |
| SCHEMBL23629399 | 0.77 | L3MBTL1 (0.50) | L3MBTL1ACHEBRD4CREBBPKMT2A | |
| SCHEMBL29374710 | 0.75 | L3MBTL1 (0.57) | L3MBTL1ACHEBRD4CREBBPKMT2A | |
| SCHEMBL1055676 | 0.75 | L3MBTL1 (0.57) | L3MBTL1ACHEBRD4CREBBPKMT2A | |
| SCHEMBL1746797 | 0.75 | KMT2A (0.76) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29651126 | 0.75 | KMT2A (0.76) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29226891 | 0.74 | CCNB2 (0.41) | L3MBTL1ACHEBRD4CREBBPPIM1 | |
| SCHEMBL1196430 | 0.74 | L3MBTL1 (0.59) | L3MBTL1ACHEBRD4CREBBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389037-A1 | HPK1 INHIBITORS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389037-A1 | HPK1 INHIBITORS AND USES THEREOF | HIPK1, SIK1, PGK1 | L3MBTL1 2199/4885ACHE 4818/4885BRD4 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.