SCHEMBL24730258

SCHEMBL24730258

Clc1ccc2c(c1)-c1c(ccc3c1[nH]c1ccccc13)C2(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNE2 O96020 1/20 0.43
CDK4 P11802 1/20 0.43
CCND1 P24385 1/20 0.43
CCNE1 P24864 1/20 0.43
CDK2 P24941 1/20 0.43
CAMK2B Q13554 1/20 0.43
CAMK2G Q13555 1/20 0.43
CAMK2D Q13557 1/20 0.43
CAMK2A Q9UQM7 1/20 0.43
TDO2 P48775 3/20 0.41
IDO1 P14902 2/20 0.41
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
PGR P06401 1/20 0.37
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
PTGS2 P35354 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730261 0.86 KIF11 (0.42) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL24730283 0.85 CDK4 (0.46) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL24730298 0.82 CDK4 (0.43) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL24730286 0.81 TDO2 (0.41) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL15840171 0.80 KIF11 (0.42) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL26014320 0.79 CDK4 (0.47) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL15840203 0.76 PDK2 (0.39) TDO2IDO1PGRKIF11HTR2B
SCHEMBL15840202 0.76 PDK2 (0.39) TDO2IDO1PGRKIF11HTR2B
SCHEMBL24730268 0.76 CDK4 (0.44) CCNE2CDK4CCND1CCNE1CDK2
SCHEMBL15840146 0.74 KIF11 (0.46) CCNE2CDK4CCND1CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed
WO-2022213794-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF OCIAD1, OCIAD2, OSTC CCNE2 2189/4885CDK4 3268/4885CCND1 1456/4885
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF OCIAD1, OCIAD2, EPCAM CCNE2 233/4885CDK4 1919/4885CCND1 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.