Sugi Predict

Sugi Predict / Compounds / SCHEMBL24730264

SCHEMBL24730264

SCHEMBL24730264

Brc1cc2c(c3[nH]c4ccccc4c13)-c1ccccc1C2(c1cccc(-c2ccccc2)c1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDK4 P11802 12/20 0.37
▸ CCND1 P24385 12/20 0.37
▸ CCNE2 O96020 7/20 0.37
▸ CCNE1 P24864 7/20 0.37
▸ CDK2 P24941 7/20 0.37
▸ CAMK2B Q13554 6/20 0.37
▸ CAMK2G Q13555 6/20 0.37
▸ CAMK2D Q13557 6/20 0.37
▸ CAMK2A Q9UQM7 6/20 0.37
▸ CCNB2 O95067 5/20 0.37
▸ CDK1 P06493 5/20 0.37
▸ CCNB1 P14635 5/20 0.37
▸ CCNB3 Q8WWL7 5/20 0.37
▸ PRKACA P17612 2/20 0.37
▸ PRKACG P22612 2/20 0.37
▸ PRKACB P22694 2/20 0.37
▸ CDK5 Q00535 3/20 0.35
▸ CDK5R1 Q15078 3/20 0.35
▸ CCNA2 P20248 2/20 0.35
▸ CCNT1 O60563 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730287 0.85 CDK4 (0.41) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL16858246 0.74 PDK2 (0.44) MEN1MAPTKMT2AMAPK1HTT
SCHEMBL26246765 0.74 KDM4E (0.31) KMT2A
SCHEMBL24730269 0.73 CDK4 (0.38) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL15840171 0.72 KIF11 (0.42) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL24730434 0.72 MEN1 (0.41) MEN1MAPTKMT2AMAPK1SMN1; SMN2
SCHEMBL24730259 0.71 TDO2 (0.38) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL22150982 0.71 PDK2 (0.41) MEN1MAPTKMT2AMAPK1HTT
SCHEMBL21113548 0.71 CDK4 (0.38) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL21113544 0.71 CDK4 (0.38) CDK4CCND1CCNE2CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 — — US disclosed
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 — — US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 — — US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 — — US disclosed
WO-2022213794-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-10-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF OCIAD1, OCIAD2, OSTC CDK4 3268/4885CCND1 1456/4885CCNE2 2189/4885
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF OCIAD1, OCIAD2, EPCAM CDK4 1919/4885CCND1 172/4885CCNE2 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.