SCHEMBL24730259

SCHEMBL24730259

Brc1cc2c([nH]c3ccccc32)c2c1C(c1ccccc1-c1ccccc1)(c1ccccc1-c1ccccc1)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 2/20 0.38
IDO1 P14902 2/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CDK4 P11802 7/20 0.36
CCND1 P24385 7/20 0.36
CCNE2 O96020 3/20 0.36
CCNE1 P24864 3/20 0.36
CDK2 P24941 3/20 0.36
CDK1 P06493 3/20 0.36
CAMK2B Q13554 2/20 0.36
CAMK2G Q13555 2/20 0.36
CAMK2D Q13557 2/20 0.36
CAMK2A Q9UQM7 2/20 0.36
CCNB2 O95067 2/20 0.36
CCNB1 P14635 2/20 0.36
CCNB3 Q8WWL7 2/20 0.36
PRKACA P17612 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21941921 0.81 PGR (0.40) TDO2IDO1CDK4CCND1CCNE2
SCHEMBL24730272 0.78 KIF11 (0.37) TDO2IDO1CDK4CCND1CCNE2
SCHEMBL24730282 0.76 BCHE (0.38) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL28489940 0.74 ESR1 (0.49) TDO2IDO1HPGDMAPK1HTT
SCHEMBL20175707 0.73 KIF11 (0.39) TDO2IDO1HPGDMAPK1CDK4
SCHEMBL17379764 0.72 CDK4 (0.39) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL24730264 0.71 CDK4 (0.37) TDO2IDO1HPGDMAPK1HTT
SCHEMBL15840202 0.71 PDK2 (0.39) TDO2IDO1HPGDMAPK1HTT
SCHEMBL15840203 0.71 PDK2 (0.39) TDO2IDO1HPGDMAPK1HTT
SCHEMBL15840146 0.70 KIF11 (0.46) TDO2HPGDMAPK1CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed
WO-2022213794-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF OCIAD1, OCIAD2, EPCAM TDO2 2037/4885IDO1 3587/4885HPGD 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.