Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.61 |
| ▸ | SCD | O00767 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947379 | 0.89 | HSD17B10 (0.65) | LRRK2HSD17B10HTTHSD17B1HSD17B2 | |
| SCHEMBL24729223 | 0.89 | HSD17B10 (0.65) | LRRK2HSD17B10HTTHSD17B1HSD17B2 | |
| SCHEMBL29947421 | 0.87 | HSD17B1 (0.81) | LRRK2HSD17B10HTTHSD17B1HSD17B2 | |
| SCHEMBL24729364 | 0.87 | HSD17B1 (0.81) | LRRK2HSD17B10HTTHSD17B1HSD17B2 | |
| SCHEMBL13329184 | 0.87 | HSD17B1 (0.81) | LRRK2HTTMAPTLMNAHSD17B1 | |
| SCHEMBL12199320 | 0.87 | HSD17B1 (0.81) | LRRK2HTTMAPTLMNAHSD17B1 | |
| SCHEMBL12199338 | 0.86 | HPGDS (0.69) | LRRK2HSD17B10HTTMAPTLMNA | |
| SCHEMBL13329187 | 0.86 | HPGDS (0.69) | LRRK2HSD17B10HTTMAPTLMNA | |
| SCHEMBL5445832 | 0.86 | HPGDS (0.69) | LRRK2HTTMAPTLMNAHSD17B1 | |
| SCHEMBL24729401 | 0.85 | HSD17B10 (0.67) | LRRK2HSD17B10HTTMAPTHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |